MODEL PERFORMANCE ANALYSIS AND MODEL VALIDATION IN LOGISTIC REGRESSION


A One-Health evaluation of the burden of cystic echinococcosis and its prevention costs: Case study from a hypo-endemic area in Italy

An integrated model, based on a One Health approach, was implemented to estimate the epidemiological and economic outcomes of cystic echinococcosis (CE) in Veneto region, an hypo-endemic area of Northern Italy, and the costs for its prevention.Data and information needed to populate the model were retrieved from published literature, official stati

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Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD

Abstract The abnormal aggregation of TDP-43 into cytoplasmic inclusions in affected neurons is a major pathological hallmark of amyotrophic lateral sclerosis click here (ALS) and frontotemporal dementia (FTD).Although TDP-43 is aberrantly accumulated in the neurons of most patients with sporadic ALS/FTD and other TDP-43 proteinopathies, how TDP-43

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Orthohantavirus diversity in Central-East Argentina: Insights from complete genomic sequencing on phylogenetics, Geographic patterns and transmission scenarios.

Hantavirus Pulmonary Syndrome (HPS), characterized by its high fatality rate, poses a significant public health concern in Argentina due to the increasing evidence of person-to-person transmission of Andes virus.Several orthohantaviruses were described in the country, but their phylogenetic relationships were inferred from partial genomic sequences

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Regulation of MntH by a dual Mn(II)- and Fe(II)-dependent transcriptional repressor (DR2539) in Deinococcus radiodurans.

The high intracellular Mn/Fe ratio observed within the bacteria Deinococcus radiodurans cga 200 to cga 510 adapter may contribute to its remarkable resistance to environmental stresses.We isolated DR2539, a novel regulator of intracellular Mn/Fe homeostasis in D.radiodurans.Electrophoretic gel mobility shift assays (EMSAs) revealed that DR2539 bind

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